human GPD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GPD1.
shAAV-210223
AAV-h-GPD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GPD1 (glycerol-3-phosphate dehydrogenase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GPD-C; GPDH-C; HTGTI
Description (Vector)
GPD1 encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
2819
Gene Name (Vector)
glycerol-3-phosphate dehydrogenase 1
Gene Symbol
GPD1
HGNC ID
HGNC:4455
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_005276
RefSeq Synonyms
NM_005276, NM_001257199, BC032234,
Species
human
UniGene ID
Hs.524418
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.