human GPA33 shRNA silencing AAV

Name 
AAV-h-GPA33-shRNA
Cat No 
shAAV-210194
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GPA33.

shAAV-210194
AAV-h-GPA33-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GPA33 (glycoprotein A33). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A33
Description (Vector)
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
Gene ID
10223
Gene Name (Vector)
glycoprotein A33
Gene Symbol
GPA33
HGNC ID
HGNC:4445
ORF Size (aa)
960
RefSeq ID
NM_005814
RefSeq Synonyms
NM_005814, BC107165, BC107164, BC074876, BC074830, BC069789, BC069761, BC069745, BC069723, BC069705,
Species
human
UniGene ID
Hs.651244

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.