human GNLY shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GNLY.
shAAV-210130
AAV-h-GNLY-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GNLY (granulysin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D2S69E; LAG-2; LAG2; NKG5; TLA519
Description (Vector)
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
10578
Gene Name (Vector)
granulysin
Gene Symbol
GNLY
HGNC ID
HGNC:4414
ORF Size (aa)
438
RefSeq ID
NM_006433
RefSeq Synonyms
NM_012483, NM_006433, NM_001302758, BC023576,
Species
human
UniGene ID
Hs.105806
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.