human GNG5 shRNA silencing AAV

Name
AAV-h-GNG5-shRNA

Cat No
shAAV-210117

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GNG5.

shAAV-210117

AAV-h-GNG5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GNG5 (G protein subunit gamma 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 (PubMed 3113327); summary by Ahmad et al., 1995) (PubMed 7606925).(supplied by OMIM, Nov 2010)

Gene ID

2787

Gene Name (Vector)

G protein subunit gamma 5

Gene Symbol

GNG5

HGNC ID

HGNC:4408

ORF Size (aa)

207

RefSeq ID

NM_005274

RefSeq Synonyms

NM_005274, BC003563,

Species

human

UniGene ID

Hs.645427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.