human GLIS3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GLIS3.
shAAV-209978
AAV-h-GLIS3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GLIS3 (GLIS family zinc finger 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NDH; ZNF515
Description (Vector)
GLIS3 is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.
Gene ID
169792
Gene Name (Vector)
GLIS family zinc finger 3
Gene Symbol
GLIS3
HGNC ID
HGNC:28510
ORF Size (aa)
2328
ORF Size (bp)
2328 bp
RefSeq ID
NM_152629
RefSeq Synonyms
NM_152629, NM_001042413, BC033899,
Species
human
UniGene ID
Hs.644570
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.