human GLIPR1 shRNA silencing AAV

Name 
AAV-h-GLIPR1-shRNA
Cat No 
shAAV-209970
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GLIPR1.

shAAV-209970
AAV-h-GLIPR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GLIPR1 (GLI pathogenesis related 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CRISP7; GLIPR; RTVP1
Description (Vector)
GLIPR1 encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. GLIPR1 is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Gene ID
11010
Gene Name (Vector)
GLI pathogenesis related 1
Gene Symbol
GLIPR1
HGNC ID
HGNC:17001
ORF Size (aa)
801
ORF Size (bp)
801 bp
RefSeq ID
NM_006851
RefSeq Synonyms
NM_006851, BC012510,
Species
human
UniGene ID
Hs.205558

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.