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human GJB4 shRNA silencing AAV

Name 
AAV-h-GJB4-shRNA
Cat No 
shAAV-209927
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GJB4.

shAAV-209927
AAV-h-GJB4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GJB4 (gap junction protein beta 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CX30.3; EKV
Description (Vector)
GJB4 encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment.
Gene ID
127534
Gene Name (Vector)
gap junction protein beta 4
Gene Symbol
GJB4
HGNC ID
HGNC:4286
ORF Size (aa)
801
ORF Size (bp)
801 bp
RefSeq ID
NM_153212
RefSeq Synonyms
NM_153212, BC034709,
Species
human
UniGene ID
Hs.715288

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.