human GJA8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GJA8.
shAAV-209918
AAV-h-GJA8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GJA8 (gap junction protein alpha 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAE; CAE1; CTRCT1; CX50; CZP1; MP70
Description (Vector)
GJA8 encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
Gene ID
2703
Gene Name (Vector)
gap junction protein alpha 8
Gene Symbol
GJA8
HGNC ID
HGNC:4281
ORF Size (aa)
1299
ORF Size (bp)
1299 bp
RefSeq ID
NM_005267
RefSeq Synonyms
NM_005267, BC146507, BC140363,
Species
human
UniGene ID
Hs.632441
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.