human GINS3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GINS3.
shAAV-209892
AAV-h-GINS3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GINS3 (GINS complex subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DNA replication complex GINS protein PSF3; GINS complex subunit 3; GINS complex subunit 3 (Psf3 homolog); PSF3
Description (eCommerce)
DNA replication complex GINS protein PSF3 is a component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. The GINS complex seems to bind preferentially to single-stranded DNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/9BRX5].
Description (Vector)
GINS3 encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
64785
Gene Name (eCommerce)
GINS complex subunit 3
Gene Name (Vector)
GINS complex subunit 3
Gene Symbol
GINS3
HGNC ID
HGNC:25851
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
651
ORF Size (bp)
651 bp
Protein Name (eCommerce)
DNA replication complex GINS protein PSF3
RefSeq ID
NM_022770
RefSeq Synonyms
NM_022770, NM_001126130, NM_001126129, BC014437, BC005879,
Research Areas
Cell Cycle,DNA Replication,Replication
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
DNA replication complex GINS protein PSF3 is a component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. The GINS complex seems to bind preferentially to single-stranded DNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/9BRX5].
UniGene ID
Hs.605546
UniProt ID (eCommerce)
Q9BRX5
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.