human GINS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GINS1.
shAAV-209888
AAV-h-GINS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GINS1 (GINS complex subunit 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DNA replication complex GINS protein PSF1; GINS complex subunit 1; GINS complex subunit 1 (Psf1 homolog); IMD55; partner of sld five-1; PSF1
Description (eCommerce)
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]) [taken from NCBI Entrez Gene (Gene ID: 9837)].
Description (Vector)
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 (PubMed 16287864)).(supplied by OMIM, Mar 2008)
Gene ID
9837
Gene Name (eCommerce)
GINS complex subunit 1
Gene Name (Vector)
GINS complex subunit 1
Gene Symbol
GINS1
HGNC ID
HGNC:28980
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
591
Protein Name (eCommerce)
DNA replication complex GINS protein PSF1
RefSeq ID
NM_021067
RefSeq Synonyms
NM_021067, BC012542,
Research Areas
Cell Cycle,DNA Replication,Replication
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]) [taken from NCBI Entrez Gene (Gene ID: 9837)].
UniGene ID
Hs.658464
UniProt ID (eCommerce)
Q14691
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.