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human GGTLC2 shRNA silencing AAV

Name 
AAV-h-GGTLC2-shRNA
Cat No 
shAAV-209856
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GGTLC2.

shAAV-209856
AAV-h-GGTLC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GGTLC2 (gamma-glutamyltransferase light chain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GGTL4
Description (Vector)
Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 (PubMed 18357469)).(supplied by OMIM, Oct 2008)
Gene ID
91227
Gene Name (Vector)
gamma-glutamyltransferase light chain 2
Gene Symbol
GGTLC2
HGNC ID
HGNC:18596
ORF Size (aa)
657
ORF Size (bp)
657 bp
RefSeq ID
NM_199127
RefSeq Synonyms
NM_199127, NM_001282879, BC069534,
Species
human
UniGene ID
Hs.632765

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.