human GGA2 shRNA silencing AAV

Name
AAV-h-GGA2-shRNA

Cat No
shAAV-209838

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GGA2.

shAAV-209838

AAV-h-GGA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

VEAR

Description (Vector)

GGA2 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.

Gene ID

23062

Gene Name (Vector)

golgi associated, gamma adaptin ear containing, ARF binding protein 2

Gene Symbol

GGA2

HGNC ID

HGNC:16064

ORF Size (aa)

1842

ORF Size (bp)

1842 bp

RefSeq ID

NM_015044

RefSeq Synonyms

NM_015044, BC000284,

Species

human

UniGene ID

Hs.460336

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.