human DLST Over-expression AAV

Name 
AAV-h-DLST
Cat No 
AAV-207063
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DLST.

AAV-207063
AAV-h-DLST

Ready-to-use AAV expressing Human DLST (dihydrolipoamide S-succinyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2-oxoglutarate dehydrogenase complex component E2; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; DLTS; E2K; OGDC-E2
Description (eCommerce)
DLST is a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) [taken from NCBI Entrez Gene (Gene ID: 1743)].
Description (Vector)
DLST encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene.
Gene ID
1743
Gene Name (eCommerce)
dihydrolipoamide S-succinyltransferase
Gene Name (Vector)
dihydrolipoamide S-succinyltransferase
Gene Symbol
DLST
HGNC ID
HGNC:2911
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
Protein Name (eCommerce)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
RefSeq ID
NM_001933
RefSeq Synonyms
NM_001933, NM_001244883, BC001922, BC000302,
Research Areas
Acyltransferase,Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
DLST is a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) [taken from NCBI Entrez Gene (Gene ID: 1743)].
UniGene ID
Hs.525459
UniProt ID (eCommerce)
P36957

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.