human GFM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GFM2.
shAAV-209825
AAV-h-GFM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GFM2 (G elongation factor mitochondrial 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EF-G2mt; EFG2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt
Description (Vector)
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
Gene ID
84340
Gene Name (Vector)
G elongation factor mitochondrial 2
Gene Symbol
GFM2
HGNC ID
HGNC:29682
ORF Size (aa)
2340
ORF Size (bp)
2340 bp
RefSeq ID
NM_032380
RefSeq Synonyms
NM_170691, NM_170681, NM_032380, NM_001281302, BC030612, BC015712,
Species
human
UniGene ID
Hs.277154
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.