human GFAP shRNA silencing AAV

Name 
AAV-h-GFAP-shRNA
Cat No 
shAAV-209815
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GFAP.

shAAV-209815
AAV-h-GFAP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GFAP (glial fibrillary acidic protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALXDRD
Description (Vector)
GFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
2670
Gene Name (Vector)
glial fibrillary acidic protein
Gene Symbol
GFAP
HGNC ID
HGNC:4235
ORF Size (aa)
1299
ORF Size (bp)
1299 bp
RefSeq ID
NM_002055
RefSeq Synonyms
NM_002055, NM_001242376, NM_001131019, BC041765, BC013596,
Species
human
UniGene ID
Hs.514227

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.