human GCNT1 shRNA silencing AAV

Name 
AAV-h-GCNT1-shRNA
Cat No 
shAAV-209752
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GCNT1.

shAAV-209752
AAV-h-GCNT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GCNT1 (glucosaminyl (N-acetyl) transferase 1, core 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C2GNT; C2GNT-L; C2GNT1; G6NT; NACGT2; NAGCT2
Description (Vector)
GCNT1 is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
2650
Gene Name (Vector)
glucosaminyl (N-acetyl) transferase 1, core 2
Gene Symbol
GCNT1
HGNC ID
HGNC:4203
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_001490
RefSeq Synonyms
NM_001490, NM_001097636, NM_001097635, NM_001097634, NM_001097633, BC109102, BC109101, BC074886, BC074885,
Species
human
UniGene ID
Hs.521568

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.