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human GAPDHS shRNA silencing AAV

Name 
AAV-h-GAPDHS-shRNA
Cat No 
shAAV-209640
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GAPDHS.

shAAV-209640
AAV-h-GAPDHS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GAPD2; GAPDH-2; GAPDS; HEL-S-278; HSD-35
Description (Vector)
GAPDHS encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility.
Gene ID
26330
Gene Name (Vector)
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Gene Symbol
GAPDHS
HGNC ID
HGNC:24864
ORF Size (aa)
1227
ORF Size (bp)
1227 bp
RefSeq ID
NM_014364
RefSeq Synonyms
NM_014364, BC036373,
Species
human
UniGene ID
Hs.248017

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.