human GADD45A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GADD45A.
shAAV-209541
AAV-h-GADD45A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GADD45A (growth arrest and DNA damage inducible alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DDIT1; GADD45
Description (Vector)
GADD45A is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
1647
Gene Name (Vector)
growth arrest and DNA damage inducible alpha
Gene Symbol
GADD45A
HGNC ID
HGNC:4095
ORF Size (aa)
498
RefSeq ID
NM_001924
RefSeq Synonyms
NM_001924, NM_001199742, NM_001199741, BC011757,
Species
human
UniGene ID
Hs.80409
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.