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human GABRQ shRNA silencing AAV

Name 
AAV-h-GABRQ-shRNA
Cat No 
shAAV-209533
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GABRQ.

shAAV-209533
AAV-h-GABRQ-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GABRQ (gamma-aminobutyric acid type A receptor theta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
THETA
Description (Vector)
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).
Gene ID
55879
Gene Name (Vector)
gamma-aminobutyric acid type A receptor theta subunit
Gene Symbol
GABRQ
HGNC ID
HGNC:14454
ORF Size (aa)
1899
ORF Size (bp)
1899 bp
RefSeq ID
NM_018558
RefSeq Synonyms
NM_018558, BC109211, BC109210,
Species
human
UniGene ID
Hs.283081

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.