human GABPA shRNA silencing AAV

Name
AAV-h-GABPA-shRNA

Cat No
shAAV-209501

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GABPA.

shAAV-209501

AAV-h-GABPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GABPA (GA binding protein transcription factor alpha subunit). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07

Description (Vector)

GABPA encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

Gene ID

2551

Gene Name (Vector)

GA binding protein transcription factor alpha subunit

Gene Symbol

GABPA

HGNC ID

HGNC:4071

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

RefSeq ID

NM_002040

RefSeq Synonyms

NM_002040, NM_001197297, BC035031,

Species

human

UniGene ID

Hs.473470

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.