human GAB3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GAB3.
shAAV-209489
AAV-h-GAB3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GAB3 (GRB2 associated binding protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
139716
Gene Name (Vector)
GRB2 associated binding protein 3
Gene Symbol
GAB3
HGNC ID
HGNC:17515
ORF Size (aa)
1758
ORF Size (bp)
1758 bp
RefSeq ID
NM_080612
RefSeq Synonyms
NM_080612, NM_001282283, NM_001081573, BC141539,
Species
human
UniGene ID
Hs.496982
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.