human G6PC3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human G6PC3.
shAAV-209482
AAV-h-G6PC3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human G6PC3 (glucose-6-phosphatase catalytic subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SCN4; UGRP
Description (Vector)
G6PC3 encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.
Gene ID
92579
Gene Name (Vector)
glucose-6-phosphatase catalytic subunit 3
Gene Symbol
G6PC3
HGNC ID
HGNC:24861
ORF Size (aa)
1041
ORF Size (bp)
1041 bp
RefSeq ID
NM_138387
RefSeq Synonyms
NM_138387, NM_001319945, BC021574, BC002494,
Species
human
UniGene ID
Hs.294005
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.