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human FZD3 shRNA silencing AAV

Name 
AAV-h-FZD3-shRNA
Cat No 
shAAV-209463
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FZD3.

shAAV-209463
AAV-h-FZD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FZD3 (frizzled class receptor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Fz-3
Description (Vector)
FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia.
Gene ID
7976
Gene Name (Vector)
frizzled class receptor 3
Gene Symbol
FZD3
HGNC ID
HGNC:4041
ORF Size (aa)
1998
ORF Size (bp)
1998 bp
RefSeq ID
NM_017412
RefSeq Synonyms
NM_145866, NM_017412, BC172481, BC156293,
Species
human
UniGene ID
Hs.40735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.