human FXYD3 shRNA silencing AAV

Name 
AAV-h-FXYD3-shRNA
Cat No 
shAAV-209444
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FXYD3.

shAAV-209444
AAV-h-FXYD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FXYD3 (FXYD domain containing ion transport regulator 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MAT8; PLML
Description (Vector)
FXYD3 belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. FXYD3 encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. FXYD3 may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
5349
Gene Name (Vector)
FXYD domain containing ion transport regulator 3
Gene Symbol
FXYD3
HGNC ID
HGNC:4027
ORF Size (aa)
264
RefSeq ID
NM_005971
RefSeq Synonyms
NM_021910, NM_005971, NM_001136012, NM_001136011, NM_001136010, NM_001136009, NM_001136008, NM_001136007, BC090044, BC005238,
Species
human
UniGene ID
Hs.301350

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.