human FUT8 shRNA silencing AAV

Name
AAV-h-FUT8-shRNA

Cat No
shAAV-209429

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human FUT8.

shAAV-209429

AAV-h-FUT8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FUT8 (fucosyltransferase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

FUT8 encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.

Gene ID

2530

Gene Name (Vector)

fucosyltransferase 8

Gene Symbol

FUT8

HGNC ID

HGNC:4019

ORF Size (aa)

927

ORF Size (bp)

927 bp

RefSeq ID

NM_004480

RefSeq Synonyms

NM_178156, NM_178155, NM_004480, BC142958,

Species

human

UniGene ID

Hs.654961

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.