human FMO2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FMO2.
shAAV-209181
AAV-h-FMO2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FMO2 (flavin containing monooxygenase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FMO1B1
Description (Vector)
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Gene ID
2327
Gene Name (Vector)
flavin containing monooxygenase 2
Gene Symbol
FMO2
HGNC ID
HGNC:3770
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
RefSeq ID
NM_001460
RefSeq Synonyms
NM_001460, NM_001301347, BC005894,
Species
human
UniGene ID
Hs.144912
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.