human FLI1 shRNA silencing AAV

Name 
AAV-h-FLI1-shRNA
Cat No 
shAAV-209083
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FLI1.

shAAV-209083
AAV-h-FLI1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FLI1 (Fli-1 proto-oncogene, ETS transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EWSR2; SIC-1
Description (Vector)
FLI1 encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
Gene ID
2313
Gene Name (Vector)
Fli-1 proto-oncogene, ETS transcription factor
Gene Symbol
FLI1
HGNC ID
HGNC:3749
ORF Size (aa)
1359
ORF Size (bp)
1359 bp
RefSeq ID
NM_002017
RefSeq Synonyms
NM_002017, NM_001271012, NM_001271010, NM_001167681, BC010115, BC001670,
Species
human
UniGene ID
Hs.504281

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.