human FKRP shRNA silencing AAV

Name 
AAV-h-FKRP-shRNA
Cat No 
shAAV-209073
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FKRP.

shAAV-209073
AAV-h-FKRP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FKRP (fukutin related protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LGMD2I; MDC1C; MDDGA5; MDDGB5; MDDGC5
Description (Vector)
FKRP encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
79147
Gene Name (Vector)
fukutin related protein
Gene Symbol
FKRP
HGNC ID
HGNC:17997
ORF Size (aa)
1488
ORF Size (bp)
1488 bp
RefSeq ID
NM_024301
RefSeq Synonyms
NM_024301, NM_001039885, BC002612,
Species
human
UniGene ID
Hs.515493

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.