human FKBP1B shRNA silencing AAV

Name
AAV-h-FKBP1B-shRNA

Cat No
shAAV-209059

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human FKBP1B.

shAAV-209059

AAV-h-FKBP1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FKBP1B (FK506 binding protein 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FKBP12.6; FKBP1L; OTK4; PKBP1L; PPIase

Description (Vector)

FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.

Gene ID

2281

Gene Name (Vector)

FK506 binding protein 1B

Gene Symbol

FKBP1B

HGNC ID

HGNC:3712

ORF Size (aa)

243

RefSeq ID

NM_004116

RefSeq Synonyms

NM_054033, NM_004116, NM_001322964, NM_001322963, BC002614,

Species

human

UniGene ID

Hs.709461

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.