human FGF5 shRNA silencing AAV

Name
AAV-h-FGF5-shRNA

Cat No
shAAV-208974

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FGF5.

shAAV-208974

AAV-h-FGF5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FGF5 (fibroblast growth factor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HBGF-5; Smag-82; TCMGLY

Description (Vector)

FGF5 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

2250

Gene Name (Vector)

fibroblast growth factor 5

Gene Symbol

FGF5

HGNC ID

HGNC:3683

ORF Size (aa)

807

ORF Size (bp)

807 bp

RefSeq ID

NM_004464

RefSeq Synonyms

NM_033143, NM_004464, NM_001291812, BC131502, BC074859, BC074858,

Species

human

UniGene ID

Hs.37055

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.