human FGF3 shRNA silencing AAV

Name
AAV-h-FGF3-shRNA

Cat No
shAAV-208971

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FGF3.

shAAV-208971

AAV-h-FGF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FGF3 (fibroblast growth factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HBGF-3; INT2

Description (Vector)

FGF3 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

Gene ID

2248

Gene Name (Vector)

fibroblast growth factor 3

Gene Symbol

FGF3

HGNC ID

HGNC:3681

ORF Size (aa)

720

ORF Size (bp)

720 bp

RefSeq ID

NM_005247

RefSeq Synonyms

NM_005247, BC113739,

Species

human

UniGene ID

Hs.37092

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.