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human FGF1 shRNA silencing AAV

Name 
AAV-h-FGF1-shRNA
Cat No 
shAAV-208942
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FGF1.

shAAV-208942
AAV-h-FGF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FGF1 (fibroblast growth factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1
Description (Vector)
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
Gene ID
2246
Gene Name (Vector)
fibroblast growth factor 1
Gene Symbol
FGF1
HGNC ID
HGNC:3665
ORF Size (aa)
468
RefSeq ID
NM_033137
RefSeq Synonyms
NM_033137, NM_033136, NM_001257212, NM_001257211, NM_001257210, NM_001257209, NM_001257208, NM_001257207, NM_001257206, NM_001257205, NM_001144935, NM_001144934, NM_001144892, NM_000800, BC032697,
Species
human
UniGene ID
Hs.483635

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.