human FEV shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FEV.
shAAV-208918
AAV-h-FEV-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FEV (FEV, ETS transcription factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSRNAFEV; PET-1
Description (Vector)
FEV belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. FEV is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
Gene ID
54738
Gene Name (Vector)
FEV, ETS transcription factor
Gene Symbol
FEV
HGNC ID
HGNC:18562
ORF Size (aa)
717
ORF Size (bp)
717 bp
RefSeq ID
NM_017521
RefSeq Synonyms
NM_017521, BC023511,
Species
human
UniGene ID
Hs.234759
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.