human FERMT3 shRNA silencing AAV

Name
AAV-h-FERMT3-shRNA

Cat No
shAAV-208910

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FERMT3.

shAAV-208910

AAV-h-FERMT3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FERMT3 (fermitin family member 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF

Description (Vector)

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

83706

Gene Name (Vector)

fermitin family member 3

Gene Symbol

FERMT3

HGNC ID

HGNC:23151

ORF Size (aa)

1992

ORF Size (bp)

1992 bp

RefSeq ID

NM_031471

RefSeq Synonyms

NM_178443, NM_031471, BC015584, BC013366, BC004347,

Species

human

UniGene ID

Hs.180535

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.