human FARS2 shRNA silencing AAV

Name 
AAV-h-FARS2-shRNA
Cat No 
shAAV-208716
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FARS2.

shAAV-208716
AAV-h-FARS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COXPD14; FARS1; HSPC320; PheRS; SPG77
Description (Vector)
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.
Gene ID
10667
Gene Name (Vector)
phenylalanyl-tRNA synthetase 2, mitochondrial
Gene Symbol
FARS2
HGNC ID
HGNC:21062
ORF Size (aa)
1356
ORF Size (bp)
1356 bp
RefSeq ID
NM_006567
RefSeq Synonyms
NM_006567, NM_001318872, BC021112, BC020239,
Species
human
UniGene ID
Hs.484547

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.