human DGKZ Over-expression AAV

Name
AAV-h-DGKZ

Cat No
AAV-206928

Availability
4-5 weeks

This is an AAV expressing Human DGKZ.

AAV-206928

AAV-h-DGKZ

Ready-to-use AAV expressing Human DGKZ (diacylglycerol kinase zeta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DAG kinase zeta; DAGK5; DAGK6; DGK-ZETA; diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; diglyceride kinase zeta; hDGKzeta

Description (eCommerce)

Diacylglycerol kinase, zeta, belongs to the eukaryotic diacylglycerol kinase family, a family of enzymes that convert DAG to phosphatidic acid (PA).

Description (Vector)

DGKZ belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.

Gene ID

8525

Gene Name (eCommerce)

diacylglycerol kinase zeta

Gene Name (Vector)

diacylglycerol kinase zeta

Gene Symbol

DGKZ

HGNC ID

HGNC:2857

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2790

ORF Size (bp)

2790 bp

Protein Name (eCommerce)

Diacylglycerol kinase zeta

RefSeq ID

NM_003646

RefSeq Synonyms

NM_201533, NM_201532, NM_003646, NM_001199268, NM_001199267, NM_001199266, NM_001105540, BC041770,

Research Areas

Cell Cycle,DNA Damage/Repair,GPCR Signaling,Metabolism/Metabolic Process,Signal Transduction,Zinc-finger

Research Areas (Faceted)

signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction,metabolism,cell_biology

Species

human

Target Sentence

Diacylglycerol kinase, zeta, belongs to the eukaryotic diacylglycerol kinase family, a family of enzymes that convert DAG to phosphatidic acid (PA).

UniGene ID

Hs.502461

UniProt ID (eCommerce)

Q13574

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.