human EXT1 shRNA silencing AAV

Name 
AAV-h-EXT1-shRNA
Cat No 
shAAV-208199
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EXT1.

shAAV-208199
AAV-h-EXT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EXT1 (exostosin glycosyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EXT; LGCR; LGS; TRPS2; TTV
Description (Vector)
EXT1 encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.
Gene ID
2131
Gene Name (Vector)
exostosin glycosyltransferase 1
Gene Symbol
EXT1
HGNC ID
HGNC:3512
ORF Size (aa)
2241
ORF Size (bp)
2241 bp
RefSeq ID
NM_000127
RefSeq Synonyms
NM_000127, BC001174,
Species
human
UniGene ID
Hs.492618

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.