human EXOSC3 shRNA silencing AAV

Name 
AAV-h-EXOSC3-shRNA
Cat No 
shAAV-208189
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EXOSC3.

shAAV-208189
AAV-h-EXOSC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EXOSC3 (exosome component 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
62
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA3J10.7; CGI-102; exosome complex component RRP40; exosome complex exonuclease RRP40; Exosome component 3; hRrp-40; p10; PCH1B; ribosomal RNA-processing protein 40; RRP40; Rrp40p
Description (eCommerce)
Exosome component 3 (EXOSC3) a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities [taken from NCBI Entrez Gene (Gene ID: 51010)].
Description (Vector)
EXOSC3 encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
51010
Gene Name (eCommerce)
exosome component 3
Gene Name (Vector)
exosome component 3
Gene Symbol
EXOSC3
HGNC ID
HGNC:17944
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
828
ORF Size (bp)
828 bp
Protein Name (eCommerce)
Exosome complex component RRP40
RefSeq ID
NM_001002269
RefSeq Synonyms
NM_016042, NM_001002269, BC008880, BC002437,
Research Areas
Gene Expression,mRNA Binding,RNA Binding,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Exosome component 3 (EXOSC3) a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities [taken from NCBI Entrez Gene (Gene ID: 51010)].
UniGene ID
Hs.713483
UniProt ID (eCommerce)
Q9NQT5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.