human ESX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ESX1.
shAAV-208128
AAV-h-ESX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ESX1 (ESX homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ESX1L; ESXR1
Description (Vector)
ESX1 encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. ESX1 likely plays a role in placental development and spermatogenesis.
Gene ID
80712
Gene Name (Vector)
ESX homeobox 1
Gene Symbol
ESX1
HGNC ID
HGNC:14865
ORF Size (aa)
1221
ORF Size (bp)
1221 bp
RefSeq ID
NM_153448
RefSeq Synonyms
NM_153448, BC053599, BC042633,
Species
human
UniGene ID
Hs.223782
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.