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human EPS8 shRNA silencing AAV

Name 
AAV-h-EPS8-shRNA
Cat No 
shAAV-208024
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EPS8.

shAAV-208024
AAV-h-EPS8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EPS8 (epidermal growth factor receptor pathway substrate 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DFNB102
Description (Vector)
EPS8 encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Gene ID
2059
Gene Name (Vector)
epidermal growth factor receptor pathway substrate 8
Gene Symbol
EPS8
HGNC ID
HGNC:3420
ORF Size (aa)
2469
ORF Size (bp)
2469 bp
RefSeq ID
NM_004447
RefSeq Synonyms
NM_004447, BC030010,
Species
human
UniGene ID
Hs.591160

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.