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human EPS15L1 shRNA silencing AAV

Name 
AAV-h-EPS15L1-shRNA
Cat No 
shAAV-208023
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EPS15L1.

shAAV-208023
AAV-h-EPS15L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; EPS15R; eps15-related protein
Description (eCommerce)
EPS15L1 (epidermal growth factor receptor substrate 15-like 1), also known as EPS15R (EPS15-related), is structurally related to the EPS15 protein, a protein involved in the receptor-mediated endocytosis of the EGF receptor. EPS15L1 and EPS15 both contain an EH (Eps15 homology) domain, a protein-protein interaction domain found in several proteins that participate in endocytosis, vesicle transport, and signal transduction.
Gene ID
58513
Gene Name (eCommerce)
epidermal growth factor receptor pathway substrate 15 like 1
Gene Name (Vector)
epidermal growth factor receptor pathway substrate 15 like 1
Gene Symbol
EPS15L1
HGNC ID
HGNC:24634
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2265
ORF Size (bp)
2265 bp
Protein Name (eCommerce)
Epidermal growth factor receptor substrate 15-like 1
RefSeq ID
NM_021235
RefSeq Synonyms
NM_021235, NM_001258376, NM_001258375, NM_001258374, BC142716, BC131590,
Research Areas
Cancer,EGFR Signaling,EGFR Signaling in Cancer,Signal Transduction
Research Areas (Faceted)
cancer,signal_transduction,cancer,signal_transduction
Species
human
Target Sentence
EPS15L1 (epidermal growth factor receptor substrate 15-like 1), also known as EPS15R (EPS15-related), is structurally related to the EPS15 protein, a protein involved in the receptor-mediated endocytosis of the EGF receptor. EPS15L1 and EPS15 both contain an EH (Eps15 homology) domain, a protein-protein interaction domain found in several proteins that participate in endocytosis, vesicle transport, and signal transduction.
UniGene ID
Hs.654639
UniProt ID (eCommerce)
Q9UBC2

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.