human EME2 shRNA silencing AAV

Name 
AAV-h-EME2-shRNA
Cat No 
shAAV-207873
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EME2.

shAAV-207873
AAV-h-EME2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EME2 (essential meiotic endonuclease 1 homolog 2 (S. pombe)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FLJ00151; gs125; SLX2B;
Description (Vector)
EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 (PubMed 17289582)).(supplied by OMIM, Mar 2008)
Gene ID
197342
Gene Name (Vector)
essential meiotic endonuclease 1 homolog 2 (S. pombe)
Gene Symbol
EME2
HGNC ID
HGNC:27289
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_001010865
RefSeq Synonyms
NM_001257370, NM_001010865, BC167808,
Species
human
UniGene ID
Hs.7247

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.