human EIF2B3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EIF2B3.
shAAV-207716
AAV-h-EIF2B3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIF-2B; EIF2Bgamma
Description (Vector)
EIF2B3 is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
8891
Gene Name (Vector)
eukaryotic translation initiation factor 2B subunit gamma
Gene Symbol
EIF2B3
HGNC ID
HGNC:3259
ORF Size (aa)
1206
ORF Size (bp)
1206 bp
RefSeq ID
NM_020365
RefSeq Synonyms
NM_020365, NM_001261418, NM_001166588, BC018728,
Species
human
UniGene ID
Hs.533549
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.