human EGR2 shRNA silencing AAV

Name
AAV-h-EGR2-shRNA

Cat No
shAAV-207672

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EGR2.

shAAV-207672

AAV-h-EGR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EGR2 (early growth response 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AT591; CMT1D; CMT4E; KROX20

Description (Vector)

EGR2 is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Gene ID

1959

Gene Name (Vector)

early growth response 2

Gene Symbol

EGR2

HGNC ID

HGNC:3239

ORF Size (aa)

1500

ORF Size (bp)

1500 bp

RefSeq ID

NM_000399

RefSeq Synonyms

NM_001321037, NM_001136179, NM_001136178, NM_001136177, NM_000399, BC035625,

Species

human

UniGene ID

Hs.1395

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.