human EGF shRNA silencing AAV

Name
AAV-h-EGF-shRNA

Cat No
shAAV-207655

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EGF.

shAAV-207655

AAV-h-EGF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EGF (epidermal growth factor). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HOMG4; URG

Description (Vector)

EGF encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.

Gene ID

1950

Gene Name (Vector)

epidermal growth factor

Gene Symbol

EGF

HGNC ID

HGNC:3229

ORF Size (aa)

3624

ORF Size (bp)

3624 bp

RefSeq ID

NM_001963

RefSeq Synonyms

NM_001963, NM_001178131, NM_001178130, BC113461, BC093731,

Species

human

UniGene ID

Hs.419815

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.