human EFEMP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EFEMP1.
shAAV-207616
AAV-h-EFEMP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EFEMP1 (EGF containing fibulin like extracellular matrix protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5
Description (Vector)
EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. EFEMP1 is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
Gene ID
2202
Gene Name (Vector)
EGF containing fibulin like extracellular matrix protein 1
Gene Symbol
EFEMP1
HGNC ID
HGNC:3218
ORF Size (aa)
1482
ORF Size (bp)
1482 bp
RefSeq ID
NM_001039348
RefSeq Synonyms
NM_001039349, NM_001039348, BC098561, BC014410,
Species
human
UniGene ID
Hs.76224
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.