human DEGS2 Over-expression AAV

Name 
AAV-h-DEGS2
Cat No 
AAV-206861
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DEGS2.

AAV-206861
AAV-h-DEGS2

Ready-to-use AAV expressing Human DEGS2 (delta 4-desaturase, sphingolipid 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C14orf66; DES2; FADS8
Description (Vector)
DEGS2 encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.
Gene ID
123099
Gene Name (Vector)
delta 4-desaturase, sphingolipid 2
Gene Symbol
DEGS2
HGNC ID
HGNC:20113
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_206918
RefSeq Synonyms
NM_206918, BC063598,
Species
human
UniGene ID
Hs.159643

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.