human DEGS1 Over-expression AAV

Name 
AAV-h-DEGS1
Cat No 
AAV-206860
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DEGS1.

AAV-206860
AAV-h-DEGS1

Ready-to-use AAV expressing Human DEGS1 (delta 4-desaturase, sphingolipid 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DEGS; DEGS-1; Des-1; DES1; FADS7; MIG15; MLD
Description (Vector)
DEGS1 encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.
Gene ID
8560
Gene Name (Vector)
delta 4-desaturase, sphingolipid 1
Gene Symbol
DEGS1
HGNC ID
HGNC:13709
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_003676
RefSeq Synonyms
NM_003676, NM_001321542, NM_001321541, BC000961,
Species
human
UniGene ID
Hs.299878

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.