human EDA2R shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EDA2R.
shAAV-207550
AAV-h-EDA2R-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EDA2R (ectodysplasin A2 receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EDA-A2R; EDAA2R; TNFRSF27; XEDAR
Description (Vector)
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.
Gene ID
60401
Gene Name (Vector)
ectodysplasin A2 receptor
Gene Symbol
EDA2R
HGNC ID
HGNC:17756
ORF Size (aa)
894
ORF Size (bp)
894 bp
RefSeq ID
NM_021783
RefSeq Synonyms
NM_021783, NM_001324206, NM_001324205, NM_001324204, NM_001324202, NM_001324201, NM_001324199, NM_001242310, NM_001199687, BC034919,
Species
human
UniGene ID
Hs.302017
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.