human DUSP18 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DUSP18.
shAAV-207420
AAV-h-DUSP18-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DUSP18 (dual specificity phosphatase 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DSP18; DUSP20; LMWDSP20
Description (Vector)
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 (PubMed 19228121)).(supplied by OMIM, Dec 2009)
Gene ID
150290
Gene Name (Vector)
dual specificity phosphatase 18
Gene Symbol
DUSP18
HGNC ID
HGNC:18484
ORF Size (aa)
567
ORF Size (bp)
567 bp
RefSeq ID
NM_152511
RefSeq Synonyms
NM_152511, NM_001304796, NM_001304795, NM_001304794, BC030987, BC028724,
Species
human
UniGene ID
Hs.517544
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.